Oral Condyloma Acuminatum in a 62-Year-Old Male: A Case Report with Histopathological Correlation

Abstract

Condyloma acuminatum is a sexually transmitted infection caused by the Human Papillomavirus (HPV), most commonly subtypes 6 and 11. Oral condylomata are uncommon and are frequently misdiagnosed clinically as squamous papilloma, fibroma, or verruca vulgaris. We report a case of oral condyloma acuminatum in a 62-year-old male patient who presented with a single sessile lesion in the right commissure region, with a history of smoking and alcohol use. An excisional biopsy was performed and histopathological examination confirmed the diagnosis of condyloma acuminatum based on characteristic microscopic features including koilocytic changes, hyperparakeratinization, and broad-based exophytic epithelial proliferation. This case highlights the importance of biopsy and histopathological evaluation in all oral mucosal lesions, especially in older patients with risk factors, and underscores the need for awareness of HPV-related oral lesions in dental practice.