Histopathological Spectrum of Endometrial Biopsies in Women with Abnormal Uterine Bleeding: An Age-Stratified Study

Abstract

Background: Abnormal uterine bleeding encompasses diverse endometrial conditions whose distribution may vary with age. This demonstration examined a dataset to illustrate reporting of endometrial histopathological patterns across age categories.
Methods: Fifty-eight synthetic records were categorized into ages 20–39, 40–49, and 50–69 years. Each record contained an age, principal bleeding pattern, and assigned histopathological diagnosis. Frequencies and percentages described clinical presentations and diagnostic distributions. Age-specific percentages used corresponding group denominators. No patient recruitment, biopsy examination, or inferential hypothesis testing was undertaken.
Results: Mean age was 43.0 ± 12.1 years, ranging from 20 to 68 years. The 40–49-year category comprised 28 records (48.3%), followed by 20–39 years with 18 (31.0%) and 50–69 years with 12 (20.7%). Heavy menstrual bleeding accounted for 30 records (51.7%). Proliferative endometrium was assigned to 17 records (29.3%), secretory endometrium to ten (17.2%), and disordered proliferative endometrium to eight (13.8%). Polyps and hyperplasia without atypia each accounted for six records (10.3%). Atrophy occurred in four (6.9%), atypical hyperplasia in three (5.2%), and carcinoma and chronic endometritis in two each (3.4%). Both carcinoma records belonged to the oldest category.
Conclusion: The analysis illustrates transparent presentation of age-stratified endometrial diagnoses. Its constructed distributions cannot establish disease prevalence, age associations, or clinical recommendations. Authentic patient records, verified histopathology, and appropriate statistical analysis are necessary before applying this framework to clinical research settings.