Utilization Patterns And Self-Reported Adverse Effects Of Commonly Dispensed Generic Medicines In Community Pharmacies: A Descriptive Study In Rote Ndao, Indonesia
Keywords:
Generic medicines; Adverse drug reactions; Drug utilization patterns; Community pharmacy; Pharmacovigilance.Abstract
Background: Generic medicines are widely utilized in Indonesia due to their affordability and bioequivalence to branded products. However, concerns regarding potential adverse effects persist, particularly for high-consumption drugs.
Objective: To analyze utilization patterns and self-reported adverse effects of the most frequently dispensed generic medicines in community pharmacies in Rote Ndao, Indonesia.
Methods: A six-month observational descriptive survey was conducted in high-volume pharmacies. Pharmacy sales records identified the most dispensed generic drugs, while 100 adult respondents completed structured questionnaires assessing adverse effects. Data were analyzed descriptively using frequency distributions and charts.
Results: Antibiotics (amoxicillin), analgesics/antipyretics (paracetamol, mefenamic acis), and antihistamines (chlorpheniramine maleate) were the most frequently dispensed medicines. Most respondents did not report significant adverse effects. Mild symptoms such as nausea, diarrhea, dizziness, drowsiness, and dry mouth were occasionally reported. Severe reactions, including serious allergic responses or hospitalization, were rare. Cold medications were more commonly associated with drowsiness compared to other drug groups.
Conclusion: Commonly dispensed generic medicines in Rote Ndao demonstrated a generally favorable safety profile, with predominantly mild and self-limiting adverse effects. These findings support the continued use of generic medicines while emphasizing the importance of rational drug use, patient counseling, and pharmacovigilance monitoring.
